Bhaktivedanta VedaBase: Śrīmad Bhāgavatam 5.5.27

mano-vaco-dṛk-karaṇehitasya

sākṣāt-kṛtaḿ me paribarhaṇaḿ hi

vinā pumān yena mahā-vimohāt

kṛtānta-pāśān na vimoktum īśet

SYNONYMS

manaḥ — mind; vacaḥ — words; dṛk — sight; karaṇa — of the senses; īhitasya — of all activities (for maintenance of body, society, friendship and so on); sākṣāt-kṛtam — directly offered; me — of Me; paribarhaṇam — worship; hi — because; vinā — without; pumān — any person; yena — which; mahā-vimohāt — from the great illusion; kṛtānta-pāśāt — exactly like the stringent rope of Yamarāja; na — not; vimoktum — to become free; īśet — becomes able.

TRANSLATION

The true activity of the sense organs — mind, sight, words and all the knowledge-gathering and working senses — is to engage fully in My service. Unless his senses are thus engaged, a living entity cannot think of getting out of the great entanglement of material existence, which is exactly like Yamarāja's stringent rope.

PURPORT

As stated in the Nārada-pañcarātra:

sarvopādhi-vinirmuktaḿ

tat-paratvena nirmalam

hṛṣīkeṇa hṛṣīkeśa-

sevanaḿ bhaktir ucyate

[Cc. Madhya 19.170]

This is the conclusion of bhakti. All the time, Lord Ṛṣabhadeva has been stressing devotional service, and now He is concluding by saying that all the senses should be engaged in the Lord's service. There are five senses by which we gather knowledge and five senses with which we work. These ten senses and the mind should be fully engaged in the Lord's service. Without engaging them in this way, one cannot get out of the clutches of māyā.

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His Divine Grace A. C. Bhaktivedanta Swami Prabhupāda, Founder Ācārya of the International Society for Krishna Consciousness